Blood thickening tied to gender-affirming testosterone is rare

People who take testosterone as gender-affirming care face a risk that the hormone will thicken their blood, leading to a side effect that requires bloodletting treatment. But now, the largest study of its kind in the U.S. suggests that this effect is actually far less common than previously thought.

In revealing that the side effect is rare, the study assuages one of the few medical concerns that come with gender-affirming testosterone, co-senior study author Dr. Daniel Slack, a second-year endocrinology fellow at Mount Sinai Hospital in New York, told Live Science.

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