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COVID-19 Vaccine Effectiveness | CDC


Results of vaccine effectiveness studies are critical to the CDC’s vaccine program and national vaccine policy decision-making.

The overall goal of CDC’s vaccine effectiveness program is to generate the comprehensive evidence needed to inform COVID-19 vaccine policy decisions and CDC guidance on other prevention measures. To accomplish this, CDC in collaboration with public health and academic partners, conducts observational studies to evaluate the real-world effectiveness of authorized and licensed COVID-19 vaccines in the United States.

CDC is committed to routinely evaluating vaccine effectiveness to detect changes that could be due to:

  • Emerging SARS-CoV-2 variants
  • Waning of vaccine protection

This work helps CDC identify population subgroups who may benefit from additional doses in the future.

Updates summarizing the results of CDC led vaccine effectiveness evaluations are provided on COVID Data Tracker.



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