Vitamin B12, Folic Acid, & Choline May Protect An Aging Brain
In the brain, 1C metabolism plays an important role in methylation, the breakdown of fats, and DNA repair.
Vitamin B12, folate (aka vitamin B9), and choline are all highly influential in these pathways—primarily through their role in the methylation of homocysteine to methionine.
So low intake levels of these nutrients (or poor absorption of them), can lead to high homocysteine levels and negatively impact the brain.
While these nutrients are found naturally in the diet, this new review summarizes the important role of supplementation for additional health benefits.